Blar i NTNU Open på forfatter "Austli, Guro Buaas"
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Lipase Catalyzed Synthesis of Enantiopure Precursors and Derivatives for β-Blockers Practolol, Pindolol and Carteolol
Gundersen, Morten Andre; Austli, Guro Buaas; Løvland, Sigrid Sløgedal; Hansen, Mari Bergan; Rødseth, Mari; Jacobsen, Elisabeth Egholm (Peer reviewed; Journal article, 2021)Sustainable methods for producing enantiopure drugs have been developed. Chlorohydrins as building blocks for several β-blockers have been synthesized in high enantiomeric purity by chemo-enzymatic methods. The yield of ... -
Synthesis of Enantiopure β-Blocker (S)-Practolol by Lipase Catalysis
Austli, Guro Buaas (Master thesis, 2018)Finding a more environmentally friendly method for synthesis of enantiopure drugs is important, due to the principles of green chemistry and to avoid potential side effects from racemic drugs. The aim for this thesis was ...